Comparison of ceftriaxone with cefotaxime in serious chest infections.
نویسندگان
چکیده
Ceftriaxone is a new, third-generation cephalosporin that, because of its long half-life, offers potential advantages of cost and convenience over similar agents such as cefotaxime. We compared the two drugs in a prospective, randomized study of the treatment of chest infections in seriously ill patients. Fifty-one patients (90 percent of whom were mechanically ventilated) received either ceftriaxone, 2g IV once daily, or cefotaxime, 2 g IV thrice daily, for five days. The two groups of patients appeared demographically comparable. Ceftriaxone in a single daily dose of 2 g once daily may not be satisfactory for the treatment of serious chest infections.
منابع مشابه
Comparison of Ceftriaxone with Cefotaxime in Serious Chest lnfections*
C hest infection is one of the most common complications in critically ill patients. ‘ It may be the primary cause of the patient’s serious illness. More frequently, patients in an ICU who are already seriously ill or injured develop a supervening chest infection, which then becomes a source of significantly increased morbidity and mortality.2’3 Chest infection in the seriously ill is most comm...
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عنوان ژورنال:
- Chest
دوره 96 6 شماره
صفحات -
تاریخ انتشار 1989